Chromosomal instability and chromosomal alterations are key drivers of tumour initiation, evolution, heterogeneity, and response to therapy. From aneuploidy and translocations to chromothripsis and ecDNA formation, cancer cells frequently experience catastrophic genomic events that reshape their genome and massively change their phenotype.

To explore this topic, this conference will bring together leading experts in Berlin, Germany. Join us to hear about the mechanisms, consequences, and therapeutic vulnerabilities associated with genomic rearrangements and to learn about how chromosomal chaos shapes cancer biology and opens new avenues for clinical intervention.

The target audience for this conference is basic and translational and clinicians, both senior and young investigators from academia and industry, who are interested in various aspects of chromosome biology as it relates to cancer.