Receptor Tyrosine Kinases (RTKs) are cell-surface receptors that, upon ligand binding, regulate cell-to-cell communication during embryonic development and in adult life. Among RTKs, the twenty-two Fibroblast Growth Factors (FGFs) and five FGF Receptors play crucial roles in proliferation, migration, differentiation, and metabolism. Aberrant FGF signalling underlies genetic and metabolic disorders, age-related diseases, and cancer. Advances in structural biology, omics technologies, and disease models as well as very promising clinical trials have greatly facilitated our understanding of FGF functions. However, many outstanding questions remain unanswered, including how FGFs interact with other signaling pathways to regulate the specificity of cellular responses in development, health, and disease.

Conference Goals:

• Bring together leaders in academia, clinical medicine, and industry with an interest in FGF and other signalling pathways to foster synergistic collaborations.
• Promote cross-fertilisation of new ideas on how RTK signalling regulates pathophysiology.
• Share innovations that are impacting basic and translational signalling research.