The 7th DNA Replication/Repair Structures & Cancer Conference (7th DRRSC) on 24-28 February 2026 will bring together scientists from diverse fields to exchange cutting-edge research findings and stimulate new ideas and approaches to address the critical challenges in cancer research. Furthermore, due to the current challenging funding landscape, it is critical to form partnerships of creative talent to address large-scale problems efficiently. The meeting is designed to optimise opportunities for productive discussion, interaction, and collaboration. Conference talks and discussions will center on developing actionable mechanistic knowledge of DNA replication, transcription and repair stress responses and their inflammation impacts suitable to guide cancer research and intervention. A focus will be on leveraging the synthetic lethality concept for DDR defects. Talks will include emerging basic and clinical findings, cutting-edge trans-disciplinary methodologies and structural and mechanistic insights for dynamic complexes. The vibrant discussions and exchange of ideas will catalyse productive collaborations and offer new insights that will support research both within and between individual labs as well as across the broader scientific community.