Course Aims In this course, the state of the art of treatment with radiation oncology of major tumour sites (breast, upper GI, prostate, rectum, lung, head and neck, cervix) and palliation will be discussed on basis of the evidence. The format of the course will be a combination of lectures and case discussions. As an introduction to each tumour site, the participants have to discuss a cancer case in small groups, that will be further discussed in plenary session. In addition, the methodology of clinical research will be explained to understand how evidence based medicine is developed. Finally, basic scientific skills, e.g. critical reading, writing and basic statistics are part of the course program. This course has been listed as one of the deliverables from the EU FP7-funded EurocanPlatform project. For information on EurocanPlatform visit: http://www.eurocanplatform.eu