TP53 mutations are linked to unfavourable prognosis in chronic lymphocytic leukaemia
Prof Bradley Monk talks to ecancer for the ESMO 2021 meeting about the results from the phase III KEYNOTE-826 study which looked at the addition of pembrolizumab to chemotherapy for recurrent, persistent or metastatic cervical cancer.
He explains that this was a randomised, double-blind study of 617 patients where the addition of pembrolizumab was compared to placebo on top of carboplatin/cisplatin and paclitaxel.
Prof Monk reports that the study met primary endpoints of overall survival and progression free survival with a 33% improvement in patients that were alive at 2 years in the all-comers subgroup.
ecancer's filming has been kindly supported by Amgen through the ecancer Global Foundation. ecancer is editorially independent and there is no influence over content.
TP53 mutations are linked to unfavourable prognosis in chronic lymphocytic leukaemia
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