Isatuximab, plus bortezomib, lenalidomide, and dexamethasone shows improved PFS in frail NDMM patients
Dr Jorge Cortes speaks to ecancer about the primary analysis from the OPTIC trial, a dose-ranging study of 3 starting doses of ponatinib.
Initially, he mentions the background of the trial. Dr Cortes then discusses the methodology and results of this trial. He says; results from this OPTIC primary analysis show a trend toward dose-dependent efficacy and safety and may provide a refined understanding of the ponatinib benefit: Risk profile and its relation to dose. Mature data from continued follow-up may support an alternate dosing regimen for patients with chronic-phase chronic myeloid leukaemia (CP-CML).
ecancer's filming has been kindly supported by Amgen through the ecancer Global Foundation. ecancer is editorially independent and there is no influence over content.
Isatuximab, plus bortezomib, lenalidomide, and dexamethasone shows improved PFS in frail NDMM patients
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