CAPTIVATE: Fixed-duration first-line treatment with ibrutinib plus venetoclax for CLL/SLL

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Published: 10 Jun 2021
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Dr Rajat Bannerji - Rutgers Cancer Institute of New Jersey/RWJBarnabas Health, New Jersey, USA

Dr Rajat Bannerji speaks to ecancer about the CAPTIVATE study.

It is a trial investigating a fixed-duration first-line treatment with ibrutinib plus venetoclax for CLL/SLL.

Initially, he explains the background of the study. Dr Bannerji then discusses the methodology and results of the study.

He mentions that first-line I+V is an all-oral, once-daily, chemotherapy-free, fixed-duration regimen that provides deep, durable responses in patients with CLL/SLL, including those with genomic high-risk features.

CR, uMRD rates, PFS, and OS appear favourable.

In the end, he talks about the safety profile of I+V.

ecancer's filming has been kindly supported by Amgen through the ecancer Global Foundation. ecancer is editorially independent and there is no influence over content.