Enasidenib plus azacitidine vs azacitidine monotherapy in mutant-IDH2 ND-AML

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Published: 13 Jun 2020
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Dr Courtney DiNardo - MD Anderson Cancer Center, Houston, USA

Dr Courtney DiNardo speaks to ecancer in an online interview for the virtual EHA 2020 meeting.

She provides an overview of the trial, which is investigating enasidenib plus azacitidine versus azacitidine alone in patients with mutant-IDH2 newly diagnosed acute myeloid leukaemia (ND-AML).

Dr DiNardo outlines the design of this randomised phase II portion of the trial, and notes that this treatment combination significantly improved complete remission and overall response rates in these patients.

She also presents the toxicity profile of this novel combination, which was generally well-tolerated in this population of patients.