Immunotherapy with radiation in metastatic pancreatic and colorectal adenocarcinoma

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Published: 15 Jul 2019
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Dr Aparna Parikh - Massachusetts General Hospital Cancer Center, Boston, USA

Dr Aparna Parikh speaks to ecancer at ESMO 21st World Congress on Gastrointestinal Cancer about the use of immunotherapy and radiation in combination in metastatic pancreatic and colorectal adenocarcinoma.

She explains that phase 2 study used ipilimumab and nivolumab with radiation to stimulate an immuno response in a select amount of patients, which are exciting results considering immunotherapy alone has not generally been shown to be effective in treating these cancers.

Dr Parikh explains that the next steps are to determine the best timing and dosage of radiation in future studies, as well as becoming more adept at managing toxicity.