Venetoclax with bortezomib and dexamethasone shows good response but higher risk of treatment related death in RRMM

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Published: 15 Jun 2019
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Dr Shaji Kumar - Mayo Clinic, Rochester, USA

Dr Shaji Kumar presents results at the 2019 European Hematology Association (EHA) Annual Meeting from a study looking at the addition of venetoclax to bortezomib and dexamethasone in patients with relapsed/refractory multiple myeloma (RRMM).

The trial randomised patients between venetoclax or placebo with bortezomib and dexamethasone and although patients receiving venetoclax saw an improved response and progression-free survival, there was an increase in treatment-emergent deaths.