The content on this site is intended for healthcare professionals only
Dr Yadav Sapkota speaks to ecancer at the 2019 American Association for Cancer Research (AACR) meeting about the results from the study that performed a genetic analysis on childhood cancer survivors who had received cranial radiation.
Dr Sapkota describes the potential role of genetic predisposition in the development of strokes in childhood cancer survivors.
He also reports the examination of whole genome sequencing data from a cohort of survivors in a retrospective study, and the identification of a chromosomal locus on chromosome 5; which was strongly associated with an increased risk of stroke.
Dr Sapkota believes the discovery of this risk allele will help identify the population that are most at risk of developing strokes and will aid in the development of therapeutic interventions for these survivors.
A reproducibility study in pulmonary adenocarcinomas supports a revised classification
Advancing breast cancer treatment in Uganda by improving molecular testing
Olaparib plus ceralasertib might benefit paediatric cancer patients with DNA repair-deficient tumours
Targeting BRAF V600E in metastatic colorectal cancer: where are we today?
The advantages of IORT for early breast cancer treatment
Combination of camonsertib plus PARPi shows clinical activity in DDR-aberrant tumours
Assessment of QoL results and correlation with survival outcomes in phase III clinical trials in metastatic NSCLC
Lung cancer screening and treatment in the Philippines
SOFT study: Clinical relevance of genomic alterations in premenopausal HR+, HER2- early breast cancer
