20 year followup on high-dose chemo with HSCT in high-risk breast cancer

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Published: 25 Oct 2018
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Dr Tessa Steenbruggen - Netherlands Cancer Institute, Amsterdam, Netherlands

Dr Steenbruggen speaks with ecancer at ESMO 2018 in Munich about the results from a 20 year followup of survival data from a trial of 885 women treated with high-dose chemotherapy and stem cell transplant between 1993-1999.

She describes how survival and safety data, linked to cancer registries, shows no overall improvement compared to the 5 year results.

Women with 10 or more positive lymph nodes faired slightly better than others, the benefit in patients with 10 or more axillary lymph nodes was found to be statistically significant while the overall survival in all patients was not statistically significant.