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SETBP1 induces transcription of developmental genes

EHA 2018

14 - 17 Jun 2018

Published: 17 Jun 2018

Views: 1708

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Dr Rocco Piazza - University of Milano-Bicocca, Milan, Italy

Dr Piazza speaks with ecancer at EHA 23 about the expression and interaction of SETBP1 in driving myeloid leukaemia.

He details the network of expression, degradation and stabilisation of SETBP1 and BTRCP, which ultimately confirm that SETBP1 binds to genomic DNA and drives epigenetic mutations.

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