PDL-1 assay concordance

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Published: 20 Oct 2016
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Dr Jill Walker - AstraZeneca, UK

Dr Walker speaks with ecancertv at ESMO 2016 about the analytical consistency of four PDL-1 assays.

She describes results based on assaying samples from head and neck cancers, with three of four assays being tested reaching a high degree of result harmonisation.

Dr Marianne Ratcliffe spoke with ecancertv earlier in the year at AACR 2016 about PDL-1 assay concordance, and Dr Walker considers the advances on the data presented then, and wider adoption of immuno-oncology in the future.

PD-1 and PDL-1 expression was considered in multiple sites during ESMO 2016, including prostate cancer by Dr Julie Graff, melanoma by Dr Alexander Eggermont and lung cancer by Dr Martin Reck.