Development of a novel CD19 CAR with improved functionality

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Published: 23 Sep 2016
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Anne Kramer - PhD student, University College London, London, UK

Anne Kramer speaks with ecancertv at Childhood Cancer 2016 about her work towards an improved line of CD 19 CAR T cells.

She describes how the single-chain variable fragment (scfv) could be a site of tumour-specific binding across multiple cancer types, and the cytotoxic capabilities of CAT CAR T cells.