Intrathecal cytarabine for paediatric brain tumours

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Published: 8 Feb 2016
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Dr Irene Slavc - Medical University of Vienna, Vienna, Austria

Dr Slavc talks to ecancertv at Children with Cancer UK’s workshop on Drug Delivery in Paediatric Brain Tumours in London, UK.

In the interview she discusses the use of intrathecal cytarabine to treat children with brain tumours such as medulloblastoma.

Intrathecal cytarabine has been used for decades to treat patients with acute myeloid leukaemia who have occult or overt central nervous system (CNS) involvement.

A liposomal formulation was developed in the 1980s with the aim of providing sustained release and which makes it particularly suitable for use as an intrathecal therapy.