Subcutaneous tarlatamab shows encouraging efficacy in previously treated extensive-stage SCLC

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Published: 6 Oct 2026
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Dr Luis Paz-Ares - 12 de Octubre University Hospital, Madrid, Spain

Dr Luis Paz-Ares summarises the DELPHI-308 phase 1 trial of subcutaneous talquetamab for extensive-stage small cell lung cancer.

The study details safety, dosing, and preliminary efficacy, highlighting a 30% response rate and manageable side effects.

Dr Paz-Ares says that the findings suggest talquetamab's significant potential in treating this challenging cancer.

ecancer's filming has been kindly supported by Amgen through the ecancer Global Foundation. ecancer is editorially independent and there is no influence over content.

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