Bupropion shows benefit for cancer-related fatigue in cancer survivors

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Published: 1 Jun 2026
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Dr Luke Joseph Peppone - University of Rochester Medical Center, Rochester, USA

At ASCO 2026 Dr Luke Peppone talks to ecancer about findings from a phase III trial evaluating bupropion for the treatment of moderate to severe cancer-related fatigue in patients who had completed surgery, radiotherapy, and/or intravenous anticancer therapy.

The study demonstrated significant improvements in fatigue symptoms with bupropion compared with placebo, supporting its potential use as a treatment option for cancer-related fatigue in clinical practice.