Advancements in minimal residual disease detection in myeloma

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Published: 30 Oct 2024
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Dr Dory Abelman - University of Toronto, Ontario, Canada

Dr Dory Abelman speaks to ecancer about advancements in minimal residual disease detection in myeloma.

Traditional methods for detecting minimal residual disease in myeloma include counting cancer cells and using multi-parameter flow cytometry.

New techniques like adaptive clonal sequencing and cell-free DNA analysis improve detection by focusing on mutations.

Challenges include accessing tumour cells and differentiating mutations.

A clinical trial is validating these technologies, aiming for better patient outcomes.

Dr Ableman concludes by saying that the future lies in less invasive blood tests and enhanced DNA analysis.