Bortezomib and dexamethasone demonstrate efficacy benefit in key subgroups vs daratumumab, bortezomib, and dexamethasone in RRMM

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Published: 1 Jun 2024
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Dr Maria-Victoria Mateos - University Hospital Salamanca, Salamanca, Spain

Dr Maria-Victoria Mateos speaks to ecancer at ASCO 2024 about the results from the subgroup analysis for the phase 3 DREAMM-7 study.

This trial evaluated belantamab mafodotin plus bortezomib and dexamethasone (BVd) vs daratumumab, bortezomib, and dexamethasone (DVd) in relapsed/refractory multiple myeloma.

In the previous analysis, BVd demonstrated a statistically significant and clinically meaningful progression-free survival benefit vs standard-of-care DVd.

Dr Mateos reports that there was improvement of 23 months in patients with RRMM and over 1 prior line of treatment.