Active surveillance for oesophageal cancer shows improved HRQoL compared to standard surgery

Share :
Published: 23 Oct 2023
Views: 55
Dr Berend Van der Wilk - Erasmus MC Cancer Institute, Rotterdam, The Netherlands

Dr Berend Van der Wilk speaks to ecancer about the SANO trial which investigated neoadjuvant chemoradiotherapy followed by surgery versus active surveillance for oesophageal cancer.

He explains that a considerable amount of patients with oesophageal cancer have a pathologically complete response after neoadjuvant chemoradiotherapy and oesophagectomy. The study hypothesised that active surveillance can be an alternative for patients with clinically complete response.

The study found that after a follow-up of two years, patients undergoing active surveillance had non-inferior overall survival and improved short-term health related quality of life compared to standard surgery.