Endoxifen levels in Breast Cancer patients and testing for CYP2D6

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Published: 9 Jan 2009
Views: 18125
Dr John Hawse, Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine
Patients receiving tamoxifen therapy who can produce high levels of endoxifen have better survival than those producing low levels - why is this? Test needed for patients with CYP2D6 gene prior to administering tamoxifen