A new analysis of UK workers reveals that certain occupations may increase the risk of bladder cancer.

This work highlights that some workers are exposed to chemicals that may cause a variety of cancers, including those in the bladder. We have identified various occupations that may benefit from occupational health advice and public health measures," said Dr. James Catto, senior author of the BJU International article.

Bladder cancer (BC) is the fourth commonest male malignancy worldwide and the 9th commonest cancer within the UK.

Whilst the incidence of BC in the UK has reduced in recent years, this cancer still represents the 6th most lethal malignancy in the UK and survival rates appear to be deteriorating, in contrast to most other cancers.

The commonest cause of BC is tobacco smoking, which accounts for about 50% of cases.

The second commonest cause of BC is occupational exposure to carcinogens.

This aetiology is well known and has been subject to health and safety regulations, such as the 2002 Control of Substances Hazardous to Health Regulations in the United Kingdom.

After analyzing 25 articles, investigators found that the greatest risk of developing bladder cancer occurred in workers within the chemical, rubber, and dye industries.

In contrast, the greatest risk of death from bladder cancer was in electrical, chemical, and transport workers.

Such deaths were also higher in the North of England, probably reflecting smoking patterns and industrial distributions.

Source: BJU International