News

ENEA 2010 Thursday Oral Session

23 Sep 2010

Effects of short (6 months) and long (18 months) term treatment  with gh-receptor antagonist pegvisomant (peg) on rhythm disturbances in acromegaly

Renata Auriemma, Federico II University of Naples, Italy

 Long term treatment with pegvisomant in acromegalic patients results in significant improvement in cardiac rhythm, with low incidence of adverse events

 

Cardiovascular risk factors in treatment-resistant, active  and long-term acromegaly: comparison to matched data from the general population and the effect of disease control

Christian Berg, University Hospital of Essen, Germany

In addition to being associated with an increase risk of cardiomyopathy, patients with acromegaly also experience a significant increase in the risk of CHD.

Pegvisomant significantly reduces the risk of CV risk in acromegalic patients, particularly in patients with normalised IGF-1 levels