Determining the risk of liver cancer after recovery from hepatitis C infection

28 Jan 2022
Determining the risk of liver cancer after recovery from hepatitis C infection

An analysis was carried out on a cohort of 1,000 patients from 11 Andalusian hospitals.

The project underscores the need for personalised medicine and individual evaluation of patients with hepatitis C, even after recovering from this infection.

“After the infection is cured, the patients' prognosis changes radically, with a smaller number of patients who will suffer complications derived from the damage already suffered.

In this sense, our findings show that there are patients who remain at risk of liver cancer, despite having been cured of hepatitis C, and therefore must continue to be closely monitored, while there are others who continue with follow-up consultations but could in fact be discharged due to their low risk”, concludes Dr. Ampuero.

The combination of two steps, transient elastography and ultrasound, is described to determine patients at risk.

Current guidelines recommend follow-up after recovery based on baseline data (that is, laboratory tests or transient elastography before starting treatment), while the study proposes also considering changes after treatment for better risk stratification.

Javier Ampuero is also a professor at the University of Seville and co-researcher in charge of the SeLiver Group in the Liver Diseases area of the Seville Institute of Biomedicine (IBiS), coordinated by Manuel Romero.

Three researchers from the CIBER for Liver and Digestive Diseases participated in this study.

This study was published in The American Journal of Gastroenterology.

Source: University of Seville