Cancer is caused by genetic changes that break down normal constraints on cell growth. It is known that obesity and being overweight increases the risk of developing cancer, but the question until now has been why?
Now, researchers at University of Bergen have demonstrated that lipids associated with obesity make cancer cells more aggressive and likely to form actual tumours.
The researchers have discovered that the changed environment surrounding the cancerous cell, from a normal weight body to an overweight or obese body, pushes the cancer cell to adapt. This allows the malignant cells to form a tumour.
“This means that even in the absence of new gene mutations, obesity increases the risk that tumours will form”, says associate professor Nils Halberg.
Obesity is the cause of approximately 500,000 new cancer cases each year, a number that is expected to grow as obesity rates continues to increase.
“To scientifically dissect how these two complicated diseases interact has been extremely interesting and rewarding. Especially as this new understanding will enable researchers to design improved treatments for obese cancer patients”, Halberg adds.
The study was published in Nature Communications
Source: The University of Bergen
The World Cancer Declaration recognises that to make major reductions in premature deaths, innovative education and training opportunities for healthcare workers in all disciplines of cancer control need to improve significantly.
ecancer plays a critical part in improving access to education for medical professionals.
Every day we help doctors, nurses, patients and their advocates to further their knowledge and improve the quality of care. Please make a donation to support our ongoing work.
Thank you for your support.