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A Complete Guide on the Management of MRONJ (Medication-Related Osteonecrosis of the Jaw)

This e-learning module has been updated from the 2017 e-learning to provide a comprehensive resource for physicians in managing medication-related osteonecrosis of the jaw (MRONJ), a side effect associated with a number of bone-targeting agents approved for use in cancer patients with bone metastases.

Published September 2020.

A Complete Guide on the Management of MRONJ (Medication-Related Osteonecrosis of the Jaw)
0 CME Points

Target audience

This module is designed to support the clinical practise of oncologists, dentists, nurses and oral surgeons to aid them in developing an effective management strategy for MRONJ.

Learning objectives

By the end of this module you should be able to:

  • Describe measures to prevent MRONJ in cancer patients
  • Describe the main risk factors for MRONJ development
  • Learn when to suspect and how to arrive at an early diagnosis of MRONJ
  • Describe what is the most appropriate management of MRONJ in each patient
  • Learn how to effectively collaborate with the dentist for the successful BTA treatment of your cancer patients.  

IT Requirements

This module requires the learner to have a good, stable internet connection and can run on Internet Explorer 7 and above, Mozilla Firefox, Google Chrome and Opera on either Windows or MacOS. Flash Add-on is also required to run this module.

If you are viewing this module on an iPad (through a browser), please download the free Articulate Mobile Player beforehand. Other tablet devices may not be compatible - please check for Flash compatibility.

If you are experiencing technical difficulties, please contact and we will get back to you as soon as possible.

Disclosure policy

ecancer and everyone involved in the development of this module has no actual or potential conflict of interest whatsoever which impinges on the making, peer reviewing and dissemination of this e-learning module which was made possible through an unrestricted educational grant from Amgen.


Production of this module was funded by an unrestricted grant from Amgen.