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EACR 2012 /
Circulating metastasis-initiating cells in breast cancer

7th - 10th Jul 2012

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Published: 19.07.12
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Prof Andreas Trumpp - German Cancer Research Centre (DKFZ), Heidelberg, Germany

Prof Trumpp talks to ecancer at the 22nd European Association for Cancer Research meeting, June 2012, Barcelona, about his project identifying metasteses-initiating cells which circulate in the blood of breast cancer patients.

His team developed an assay identifying which cell starts the spread of cancer.

Blood samples from 600 patients were examined and a number of markers and receptors were identified. Cells from these samples were then planted in to mice to study the resulting bone metasteses.

The markers identified have the potential for better diagnose breast cancer patients into high and low risk groups.

Some of the receptors ID'd already have inhibitor drugs available so there is the potential for new trials looking at preventing metasteses with drugs already on the market.

 

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Founding partners

European Cancer Organisation European Institute of Oncology

Founding Charities

Foundazione Umberto Veronesi Fondazione IEO Swiss Bridge

Published by

ecancer Global Foundation