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ASCO 2019 /
A phase II study of bemcentinib with pembrolizumab in patients with advanced NSCLC

31st May - 4th Jun 2019

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Published: 11.06.19
Views: 261

Dr Enriqueta Felip - Vall d´Hebron Institute of Oncology (VHIO), Barcelona, Spain

Dr Enriqueta Felip speaks to ecancer at the 2019 American Society of Clinical Oncology (ASCO) Annual Meeting about the preliminary results from a phase II study examining the combination of bemcentinib and pembrolizumab in patients with advanced NSCLC.

She reveals that a 35 percent response rate was achieved in those patients with AXL-positive tumours. For patients with PD-L1 negative tumours, a response rate of 20 percent was seen.

Dr Felip also discusses the main adverse events associated with this combination, which included grade 3 liver toxicity - but improved with the use of steroids.

For the future, Dr Felip mentions that this particular combination may have a role specifically for patients who have been selected by AXL.

 

Previous conferences: highlights



Founding partners

European Cancer Organisation European Institute of Oncology

Founding Charities

Foundazione Umberto Veronesi Fondazione IEO Swiss Bridge

Published by

ecancer Global Foundation