ecancermedicalscience

Case Report

Targeted therapy with propranolol and metronomic chemotherapy combination: sustained complete response of a relapsing metastatic angiosarcoma

8 Jan 2015
Shripad Banavali, Eddy Pasquier, Nicolas André

We report here a case of a 69-year-old woman with a relapsing metastatic angiosarcoma treated with a combination of metronomic chemotherapy and propranolol. The beta blockers were added since the tumour was positive for betaadrenergic receptor. A complete response was quickly obtained and lasted for 20 months.

With this case, the combination of metronomic chemotherapy and propranolol in angiosarcoma warrants additional studies and illustrates the potential of metronomics to generate innovative yet inexpensive targeted therapies for both high-income and low-/middle-income countries.

Related Articles

Mevhibe B Hocaoglu, Grant Lewison, Hamish Sharp, Tania Pastrana, Eve Namisango, James Cleary, Barbara Hasties, Eric Kabisa, Helena Musau, Kathryn Spangenberg, Paola Ruiz, Zipporah Ali, Mertixell Mallafre-Larrosa, Alfredo Polo, Julie Torode, Ajay Aggarwal, Richard Sullivan
Nuradh Joseph, Vimukthini Peiris, Vodathi Bamunuarachchi, Prasad Abeysinghe, Nadarajah Jeyakumaran, Devinda Jayathilake, Kanthi Perera, Rohini Fernandopulle, Sanjeeva Gunasekera
Susan Msadabwe, Peng Yun Ng, Richard Sullivan, Kennedy Lishimpi, John Kachimba, Justor Banda, Jane Mumba, Abidan Chansa, Mutuna Chiwele, Kasonde Bowa, Kaseya Chiyenu, Linda Malulu-Chiwele, Julie Torode, Grant Lewison, Andrew Leather, Ajay Aggarwal, Kathleen Schmeler, Groesbeck Parham, Kabisa Mwala, Paul Kamfwa