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ECHELON-1 study 3 year update: Frontline brentuximab vedotin with chemotherapy for stage 3/4 classical Hodgkin lymphoma

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Published: 20.06.19
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Dr Andrea Gallamini - Centre Antoine Lacassagne, Nice, France

Dr Andrea Gallamini speaks to ecancer at the 2019 European Hematology Association (EHA) Annual Meeting about the 3 year update from the ECHELON-1 study into frontline brentuximab vedotin with chemotherapy for stage 3/4 classical Hodgkin lymphoma.

He reports that the extended follow up beyond 3 years has shown a consistent advantage of brentuximab vedotin with doxorubicin, vinblastine, and dacarbazine (A plus AVD) over doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD).

Dr Gallamini adds that the toxic profile of A plus AVD was acceptable with below 20% of patients continuing to show peripheral neuropathy.

ecancer's filming has been kindly supported by Amgen through the ecancer Global Foundation. ecancer is editorially independent and there is no influence over content.

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