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AlloHCT conditioning intensity in AML in complete remission with residual disease

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Published: 15.06.19
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Dr Christopher Hourigan - National Heart, Lung, and Blood Institute, Bethesda, USA

Dr Christopher Hourigan speaks to ecancer at the 2019 European Hematology Association (EHA) Annual Meeting about a study looking at the impact of allogeneic haematopoietic cell transplantation (alloHCT) conditioning intensity on post-transplant outcomes in acute myeloid leukaemia (AML) patients in complete remission (CR) but with pre-transplant genomic evidence of residual disease.

He explains that normally measurable residual disease in AML is measured by flow cytometry or PCR but, due to the sample, next generation sequencing was used.

Dr Hourigan reports that the patients that had no evidence of a variant detected showed equal survival regardless of which arm of transplant they were in.

ecancer's filming has been kindly supported by Amgen through the ecancer Global Foundation. ecancer is editorially independent and there is no influence over content.

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