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Highlights from ASCO 2019

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Published: 03.06.19
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Asst. Prof Bishal Gyawali and Monique Biryiana

Asst. Prof Bishal Gyawali and Monique Biryiana speak at the 2019 American Society of Clinical Oncology (ASCO) Annual Meeting about the highlights from this year's conference.

Asst. Prof Gyawali discusses several presentations that address topics ranging from racial disparities, accelerated drug approvals and the importance of assessing overall survival in clinical trials.

The presentations that he referred to are:

Affordable Care Act (ACA): Medicaid expansion impact on racial disparities in time to cancer treatment.

Phase III APACT trial: A multicentre, international, open-label, randomised trial of adjuvant nab-paclitaxel plus gemcitabine (nab-P/G) vs gemcitabine (G) for surgically resected pancreatic adenocarcinoma.

Phase III ANNOUNCE trial: A randomised, placebo (PBO)-controlled, double-blind trial of doxorubicin (dox) olaratumab versus dox PBO in patients (pts) with advanced soft tissue sarcomas (STS).

Phase III TITAN trial: A double-blind, randomised study of apalutamide (APA) versus placebo (PBO) in patients (pts) with metastatic castration-sensitive prostate cancer (mCSPC) receiving androgen deprivation therapy (ADT).

Phase III MONALEESA-7 trial: In which Dr Sara A. Hurvitz spoke with ecancer about the effect of endocrine therapy with or without ribociclib on overall survival in premenopausal patients.

Phase III POLO trial: In which Dr Hedy Kindler spoke with ecancer about the role of olaparib as a maintenance treatment following first-line, platinum- based chemotherapy in patients with a BRCA mutation and metastatic pancreatic cancer.

Phase II KEYNOTE-062 trial: In which Dr Josep Tabernero spoke with ecancer about pembrolizumab with or without chemotherapy, compared to chemotherapy alone for gastric or gastroesophageal junction adenocarcinoma.

Phase III ENZAMET trial: In which Dr Christopher Sweeney spoke with ecancer about the effect of standard-of-care therapy with or without enzalutamide for mHSPC on overall survival.

All opinions expressed in this video are the speakers own and do not reflect that of any institution.

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