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ADMIRAL: Gilteritinib as treatment for patients with relapsed or refractory acute myeloid leukaemia

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Published: 15.04.19
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Prof Alexander Perl - University of Pennsylvania, Philadelphia, USA

Prof Alexander Perl speaks to ecancer at the 2019 American Association for Cancer Research (AACR) meeting about results from the ADMIRAL trial which looked at the use of gilteritinib as treatment for patients with elapsed or refractory acute myeloid leukaemia (AML) in comparison with standard chemotherapy regimens.

He explains that patients with relapsed or refractory FLT3-mutated AML have historically had a very poor prognosis, with chemotherapy treatment generally yielding low remission rates.

Prof Perl reports that the FLT3-targeted drug gilteritinib was compared with the best available current chemotherapy treatment, with response doubled in almost every metric looked at (in favour of gilteritinib).

Read more about this research here.

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