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Phase II trial of nivolumab combined with ibrutinib for patients with Richter transformation

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Published: 17.12.18
Views: 893

Dr Nitin Jain - MD Anderson Cancer Centre, Houston, USA

Dr Nitin Jain speaks to ecancer at ASH 2018 about the trial looking at the combination of nivolumab and ibrutinib for patients with Richter transformation.

He reports that 42% of 24 patients had a response to the therapy and that 4 of the patients that had a response were then able to have an allotransplant.

Dr Jain explains that, although immune toxicity was a worry, very minimal toxicity was seen and the only side effects were from ibrutinib which they are accustomed to.

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