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Brain metastases developed from HER2 positive and triple negative breast cancer

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Published: 14.12.18
Views: 1062
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Dr Patricia Steeg - National Cancer Institute, Bethesda, USA

Dr Patricia Steeg speaks to ecancer at SABCS 2018 about how brain metastases can develop from metastatic HER2 positive and triple negative breast cancer.

She reports that a mouse model has been used in order to find a drug that can prevent brain metastases from being developed from these subtypes, with the drug temozolomide showing significant capabilities of prevention.

Dr Steeg explains that a secondary metastases prevention trial has been set up with HER2 positive breast cancer patients who already have signs of brain metastases, with a primary endpoint of no additional brain metastases. 
 

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