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The combined analysis of carfilzomib trials for multiple myeloma

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Published: 07.12.18
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Prof Maria Victoria Mateos - University of Salamanca, Salamanca, Spain

Prof Maria-Victoria Mateos speaks to ecancer at the ASH 2018 Annual Meeting about the efficacy and safety results of carfilzomib and dexmethasone in lenalidomide exposed and refractory multiple myeloma patients.

She outlines the rationale for the carfilzomib trials in the relapsed setting mentioning three specific clinical trials: ENDEAVOR, CHAMPION-1 and ARROW.

She then explains the toxicity profile of carfilzomib and concludes that it is something that could be incorporated into everyday practice, with the next step being combining carfilzomib and dexamethasone with a monoclonal antibody.

ecancer's filming has been kindly supported by Amgen through the ecancer Global Foundation. ecancer is editorially independent and there is no influence over content.

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