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Neoadjuvant ipilimumab plus nivolumab in early stage colon cancer

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Published: 22.10.18
Views: 896

Dr Myriam Chalabi - Netherlands Cancer Institute, Amsterdam, Netherlands

Dr Myriam Chalabi speaks with ecancer at ESMO 2018 in Munich about the first neoadjuvant study of anti-CTLA-4 ipilimumab plus anti-PD1 nivolumab in early stage dMMR and MMR proficient colon cancers.

She links mismatch repair status and response rates observed in 15 tumours, and describes the tolerability as a positive indicator for further research in neoadjuvant immunotherapy for these patients.

Combination immunotherapy for metastatic colorectal cancer (mCRC) is also discussed by Dr Heinz-Josef Lenz here.

ecancer's filming has been kindly supported by Amgen through the ecancer Global Foundation. ecancer is editorially independent and there is no influence over content.

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