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KEYNOTE048: First line pembrolizumab for recurrent or metastatic head and neck squamous cell carcinoma

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Published: 22.10.18
Views: 407
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Prof Barbara Burtness - Yale Cancer Center, New Haven, USA

Prof Barbara Burtness speaks with ecancer at ESMO 2018 in Munich about results from a phase III study of pembrolizumab as mono therapy and in combination with EXTREME chemotherapy.

She describes the scoring system through which PD-L1 expression was ranked, with mono therapy improving survival in both PD-L1 positive populations over chemotherapy.

Prof Burtness notes toxicity profiles compared to the chemotherapy course, and that the combination was utilised in an all-comers population, meaning a direct comparison of arms is not wholly reflective of any superior treatment schedule.

ecancer's filming has been kindly supported by Amgen through the ecancer Global Foundation. ecancer is editorially independent and there is no influence over content.

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