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6-factor prognostic model for patients with advanced urothelial carcinoma

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Published: 09.02.18
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Dr Gregory Pond - McMaster University, Hamilton, Ontario

Dr Pond speaks with ecancer at the 2018 ASCO Genitourinary Cancers Symposium about a new 6-factor prognostic model for patients with advanced urothelial carcinoma receiving post-platinum atezolizumab.

The model is based on two previous clinical trials using atezolizumab.

Six factors were deduced which were prognostic for survival.

The adverse risk factors for each of the six were identified (risk stratification) and quantified for each patients.

This was then evaluated against the second previous clinical trail dataset.

He found that those with 4 or more risk factors had a median survival of less than 3 months - which means those patients may not benefit from immunotherapy, an important factor to identify. 

 

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