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Results from the APHINITY trial of two HER2 targeted agents with chemo

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Published: 05.06.17
Views: 3592

Prof Gunter von Minckwitz - German Breast Group, Neu-Isenburg, Germany

Prof von Minckwitz speaks with ecancer at ASCO 2017 about results from the APHINITY trial, a phase III clinical trial of 4,805 women with HER2-positive breast cancer.

By adding a second HER2 targeted medicine, pertuzumab, to standard of care trastuzumab after surgery, he describes how the risk of patients developing invasive disease is reduced.

Prof von Minckwitz considers the associated toxicity of this double-hit, notably cardiac toxicities, and discusses the possible substitution of trastuzumab for a biosimilar.

For more on these results, watch his presentation of findings at a press briefing.


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