Our website uses cookies to improve your on-site experience. By using the website, cookies are being used as described in our Policy Document
Warning: To log in you will need to enable cookies and reload the page (Policy Document)
My ePortfolio Register   
 

Abstract | Full HTML Article | PDF ecancer 11 755 / https://doi.org/10.3332/ecancer.2017.755

Review

Cancer of childhood in sub-Saharan Africa

Measurement of incidence rates of childhood cancer in Africa is difficult. The study ‘Cancer of Childhood in sub Saharan Africa’ brings together results from 16 population-based registries which, as members of the African Cancer Registry Network (AFCRN), have been evaluated as achieving adequate coverage of their target population. The cancers are classified according to the third revision of the International Classification of Childhood Cancer (ICCC-3) and recorded rates in Africa are compared with those in childhood populations in the UK, France, and the USA.

It is clear that, in many centres, lack of adequate diagnostic and treatment facilities leads to under-diagnosis (and enumeration) of leukaemias and brain cancers. However, for several childhood cancers, incidence rates in Africa are higher than those in high-income countries. This applies to infection-related cancers such as Kaposi sarcoma, Burkitt lymphoma, Hodgkin lymphoma and hepatocellular carcinoma, and also to two common embryonal cancers - retinoblastoma and nephroblastoma. These (and other) observations are unlikely to be artefact, and are of considerable interest when considering possible aetiological factors, including ethnic differences in risk (and hence genetic/familial antecedents).

The data reported are the most extensive so far available on the incidence of cancer in sub Saharan Africa, and clearly indicate the need for more resources to be devoted to cancer registration, especially in the childhood age range, as part of an overall programme to improve the availability of diagnosis and treatment of this group of cancers, many of which have—potentially—an excellent prognosis.

Keywords: Cancer, incidence, childhood, sub-Saharan Africa, cancer registry

Loading Article Metrics ... Please wait

Author interviews

Max Parkin

African Cancer Registry Network, INCTR, Oxford, UK

Related articles

Conference Report: Highlights from the 2018 WIN Symposium, 25–26 June 2018, Paris: designing the future of precision oncology

Abstract | Full Article | PDF Published: 12 Sep 2018 / https://doi.org/10.3332/ecancer.2018.871

Conference Report: Inspiration, innovation and integration: highlights from the third ICPCN conference on children’s palliative care, 30th May-2nd June 2018, Durban, South Africa

Abstract | Full Article | PDF Published: 11 Sep 2018 / https://doi.org/10.3332/ecancer.2018.870

Special Issue: Pre-, pro- and synbiotics in cancer prevention and treatment—a review of basic and clinical research

Abstract | Full Article | PDF Published: 05 Sep 2018 / https://doi.org/10.3332/ecancer.2018.869

Special Issue: Gut microbiota, chemotherapy and the host: the influence of the gut microbiota on cancer treatment

Abstract | Full Article | PDF Published: 05 Sep 2018 / https://doi.org/10.3332/ecancer.2018.868

Special Issue: Moving on from Metchnikoff: thinking about microbiome therapeutics in cancer

Abstract | Full Article | PDF Published: 05 Sep 2018 / https://doi.org/10.3332/ecancer.2018.867



Founding partners

European Cancer Organisation European Institute of Oncology

Founding Charities

Foundazione Umberto Veronesi Fondazione IEO Swiss Bridge

Published by

ecancer Global Foundation