Concomitant use of antibiotics and immune checkpoint inhibitors in patients with solid neoplasms

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Published: 15 May 2020
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Dr Akhil Kapoor - Tata Memorial Center, Mumbai, India

Dr Akhil Kapoor speaks to ecancer about his article on a study looking at the concomitant use of antibiotics and immune checkpoint inhibitors in patients with solid neoplasms.

He explains that this was a retrospective audit of a prospectively collected database of patients who had received ICI for advanced solid tumours in any line between August 2015 and November 2018 at Tata Memorial Hospital in Mumbai.

Dr Kapoor reports that patients who received antibiotics for more than 10 days had an OS of 2.8 months, compared with 8.8 months for patients who received less than 10 days of antibiotics.

He explains that this shows that a longer duration of antibiotics led to poorer outcomes.

You can read the article published in ecancermedicalscience here.