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Adding lapatinib to adjuvant trastuzumab does not improve outcomes in early-stage HER2-positive breast cancer

2014 ASCO Annual Meeting

30 May - 3 Jun 2014

Published: 1 Jun 2014

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Dr Edith Perez - Mayo Clinic, Rochester, USA

At a press conference at ASCO 2014, Dr Perez presents the findings from a large phase III study, ALTTO (Adjuvant Lapatinib and/or Trastuzumab Treatment Optimisation), which suggest that post-surgery (adjuvant) treatment using a combination of two HER2-targeted drugs – trastuzumab and lapatinib – is no more effective than standard treatment with trastuzumab alone for women with early HER2-positive breast cancer.

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