Transcriptome-Wide Association Study identifies genetic factors linked to subsequent cancers in childhood cancer survivors
Prof James Brierley speaks to ecancer about the basis for updates for the 9th edition of UICC TNM classification of malignant diseases.
He explains the necessity for revisions due to expanding medical knowledge. He details the reasons for the 9th edition update, including limitations of previous versions, and emphasises the crucial role of large global databases in refining the staging system.
Prof Brierley outlines future publication strategies, moving towards open-access papers and online educational resources.
He also addresses challenges in implementing updates in resource-limited countries, the integration of prognostic factors and molecular markers, and the concept of stage migration, particularly in prostate cancer.
Transcriptome-Wide Association Study identifies genetic factors linked to subsequent cancers in childhood cancer survivors
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