This paper presents a critical synthesis of the national conference “Gastric Cancer at Ruggi d’Aragona”, held in Salerno, Italy, in June 2025. The event gathered over 200 specialists to discuss recent advances in the multidisciplinary management of gastric cancer. Key topics included precision surgery, integration of imaging and molecular profiling, innovations in minimally invasive and robotic techniques, and emerging strategies such as conversion therapy and neoadjuvant immunotherapy. Insights from the 16th International Gastric Cancer Congress highlighted global trends, including the rise of targeted and immunologic approaches and the expansion of collaborative networks. The analysis identifies gaps between technological potential and clinical implementation and outlines future priorities for research and healthcare organization. This report aims to inform clinical practice and foster interdisciplinary reflection on the evolving management of gastric cancer.