Once again, the American Association for Cancer Research (AACR) will host and organise an exciting program on the best and latest in cancer research, in which a wide swath of the cancer research community will participate, to advance the cause of treating and preventing cancer. The will reflect the AACR’s strengths in basic, translational, and clinical research, and also emphasise the productive interfaces emerging between these once-separated disciplines. The program will capture the advances on all these fronts, with a range of speakers and participants who are leaders in research: cancer mechanisms, systems approaches to cancer biology, diagnostics and therapeutics, translation of advances to the clinic, and cutting-edge science in the prevention and early interception of cancer. At the AACR 102nd Annual Meeting 2011, participants will present, discuss, and learn in a variety of settings: plenary lectures, symposia, minisymposia, workshops, poster sessions, and other formats.