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SABCS 2017 /
Postmenopausal women who lose weight may have reduced breast cancer risk

5th - 9th Dec 2017

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Published: 09.12.17
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Prof Rowan Chlebowski - City of Hope, Duarte, USA

Prof Rowan Chlebowski speaks at a SABCS 2017 press session about how postmenopausal women who lose weight may have reduced breast cancer risk.

Chlebowski and colleagues analyzed data from the Women’s Health Initiative (WHI) Observational Study.

This program tracks the health of postmenopausal women between the ages of 50 and 79. Participants who had a normal mammogram, no prior breast cancer, and were not underweight (BMI ≥ 18.5) were eligible for enrollment in Chlebowski’s study.

Measurements for height and weight were obtained upon enrollment, and measurements were reassessed three years following.

At baseline, 41 percent of women were normal weight, 34 percent were overweight, and 25 percent were obese.

Of the 61,335 patients enrolled in Chlebowski’s study, 3,061 developed invasive breast cancer during an average of 11.4 years of follow-up.

Compared to women with stable weight, those who lost weight (≥ 5 percent weight change) were 12 percent less likely to develop breast cancer following multivariable analysis.

Read the news story for more.

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Founding partners

European Cancer Organisation European Institute of Oncology

Founding Charities

Foundazione Umberto Veronesi Fondazione IEO Swiss Bridge

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Cancer Intelligence