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WIN Symposium 2017 /
Genomic analysis of childhood tumours; biological and therapeutic implications

26th - 27th Jun 2017

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Published: 04.07.17
Views: 609

Dr Peter Lichter - German Cancer Research Center (DKFZ), Heidelberg, Germany

Dr Lichter speaks with ecancer at WIN 2017 about germline mutations and heritable predispositions behind in paediatric brain cancer.

He outlines the Sonic Hedgehog family of genes as common driver in medulloblastoma, and discusses how translocation of genes to enhancer regions can trigger disease onset.

Dr Lichter notes that guidelines for treatments must reflect mutational subtypes, with patients whose tumours show enhanced activation of Wnt-Catenin signalling among the best prognosis compared to APC and Sonic subtypes.

Previous conferences: highlights

Founding partners

European Cancer Organisation European Institute of Oncology

Founding Charities

Foundazione Umberto Veronesi Fondazione IEO Swiss Bridge

Published by

Cancer Intelligence