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IMPAKT Breast Cancer Conference 2013 /
CD4 T cells in extensively inflitrated breast cancer signal organised immune response and predict survival

2nd - 4th May 2013

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Published: 15.05.13
Views: 5464

Dr Karen Willard-Gallo - Université Libre de Bruxelles, Brussels, Belgium

ecancer reporter Peter Goodwin talks to Dr Willard-Gallo at the 2013 IMPAKT conference in Brussels about IDing immune response in breast cancer, helping to asses prognosis.

CD4 T cells are critical regulators of immune responses but their functional role in breast cancer is relatively unknown. The goal of the study was to produce an image of CD4 T cells infiltrating breast tumors (TIL) using limited ex vivo manipulation to better understand the in vivo differences associated with patient prognosis.

The identification of CD4 T cells as a new key immune element in breast cancer, linked with organized immunity and associated with a higher response
rate to chemotherapy and/or excellent long-term clinical outcome, suggests that their presence in some tumours is an important prognostic factor.

ecancer's filming at IMAPKT has been kindly supported by Amgen through the ECMS Foundation. ecancer is editorially independent and there is no influence over content.

Previous conferences: highlights

Founding partners

European Cancer Organisation European Institute of Oncology

Founding Charities

Foundazione Umberto Veronesi Fondazione IEO Swiss Bridge

Published by

ecancer Global Foundation